
Random Donor Platelets (RDP)
At Uttarakhand Blood Centre, Dehradun, we provide Random Donor Platelets (RDP) for patients with low platelet counts. RDP is prepared from whole blood donations and serves as a vital component for treating thrombocytopenia and bleeding disorders.
What are Random Donor Platelets?
Random Donor Platelets (RDP) are platelet concentrates prepared from a single unit of whole blood donation. Unlike Single Donor Platelets (SDP), RDP comes from individual blood donations and typically contains 5.5-10 x 10^10 platelets per unit.
RDP Collection and Processing
RDP units are prepared through the following process:
- Whole blood (450 mL) is collected from healthy donors
- Blood is centrifuged to separate into components (red cells, plasma, platelets)
- Platelet-rich plasma is extracted and further centrifuged
- Platelets are concentrated and resuspended in plasma
- Units are stored at 20-24°C with continuous agitation for up to 5 days
Medical Uses of RDP
RDP transfusions are essential for patients with:
- Thrombocytopenia (platelet count < 50,000/μL)
- Chemotherapy-induced platelet deficiency
- Bone marrow failure or aplastic anemia
- Disseminated intravascular coagulation (DIC)
- Massive transfusion requirements
- Liver disease with platelet dysfunction
- Surgical procedures requiring platelet support
Benefits of RDP Transfusion
- Stops or prevents bleeding episodes
- Supports platelet function in surgical patients
- Essential for cancer patients undergoing treatment
- Improves coagulation in bleeding disorders
- Critical support for bone marrow transplant patients
RDP vs SDP Comparison
Key differences between Random Donor Platelets and Single Donor Platelets:
Random Donor Platelets (RDP)
- • From single whole blood donation
- • Lower platelet concentration
- • May require multiple units
- • More cost-effective
- • Readily available
Single Donor Platelets (SDP)
- • From single donor via apheresis
- • Higher platelet concentration
- • Equivalent to 6-8 RDP units
- • Reduced donor exposure
- • Preferred for repeated transfusions
Storage and Shelf Life
RDP units must be stored at 20-24°C with continuous gentle agitation to maintain platelet viability. The shelf life is limited to 5 days from collection date, after which platelets lose their effectiveness and increase infection risk.
Emergency RDP Availability in Dehradun
Uttarakhand Blood Centre maintains adequate RDP inventory for emergency situations in Dehradun. We coordinate with local hospitals for urgent platelet requirements, especially during dengue season and for oncology patients.
Quality Control Measures
All RDP units undergo strict quality testing:
- Bacterial contamination screening
- pH and platelet count verification
- Sterility testing
- ABO and Rh compatibility checking
- Storage temperature monitoring
For urgent RDP requirements or platelet transfusion services in Dehradun, contact Uttarakhand Blood Centre immediately. We ensure timely delivery to hospitals across the city.
+91 90843 11316